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#cgmp

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Daniel Prieto<p>Really proud to share this latest publication with a dream team. <br>We describe a new Drosophila stock for cGMP imaging. Plus: A microscopy approach that enables FRET analysis made easy with almost any (spectral) confocal.<br>Plus: <a href="https://mastodon.uy/tags/openaccess" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>openaccess</span></a> at really affordable fees. </p><p><a href="https://mastodon.uy/tags/uruguay" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>uruguay</span></a> <a href="https://mastodon.uy/tags/microscopy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>microscopy</span></a> <a href="https://mastodon.uy/tags/Drosophila" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Drosophila</span></a> <a href="https://mastodon.uy/tags/imaging" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>imaging</span></a> <a href="https://mastodon.uy/tags/cGMP" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cGMP</span></a> <a href="https://mastodon.uy/tags/FRET" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>FRET</span></a> <a href="https://mastodon.uy/tags/oa" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>oa</span></a> <a href="https://mastodon.uy/tags/micropublication" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>micropublication</span></a> <a href="https://mastodon.uy/tags/biology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>biology</span></a> </p><p><a href="https://micropublication.org/journals/biology/micropub-biology-000887" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">micropublication.org/journals/</span><span class="invisible">biology/micropub-biology-000887</span></a></p>
Rhyothemis<p><span class="h-card"><a href="https://mastodon.social/@inkican" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>inkican</span></a></span> </p><p>Interesting, but the article is frustratingly vague about the mechanism of action.</p><p>The drug/MoA is probably the same as in this article⬇️ <br>"PnPP-19 potentiates erection, in vivo and ex vivo, via NO/cGMP pathway, does not affect sodium channels or rat heart, and shows no toxicity and low immunogenicity, what makes it a very promising candidate as a novel drug in the therapy of erectile dysfunction."</p><p><a href="http://dx.doi.org/10.1016/j.juro.2015.06.081" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">http://</span><span class="ellipsis">dx.doi.org/10.1016/j.juro.2015</span><span class="invisible">.06.081</span></a></p><p>~<br>NO is antimicrobial and it's possible this drug could be used for other purposes.</p><p><a href="https://zeroes.ca/tags/NitricOxide" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>NitricOxide</span></a> <a href="https://zeroes.ca/tags/cGMP" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cGMP</span></a> <a href="https://zeroes.ca/tags/vasodilators" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>vasodilators</span></a> <a href="https://zeroes.ca/tags/DrugDevelopment" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>DrugDevelopment</span></a> <a href="https://zeroes.ca/tags/NaturalProducts" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>NaturalProducts</span></a> <a href="https://zeroes.ca/tags/BZ371A" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>BZ371A</span></a></p>
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