We’ve finally found out what makes #urine yellow it comes from #bacteria metabolizing waste from #redbloodcells
#Bilirubin is orange pigment released by red #bloodcells after they die. Gut microbes use bilirubin reductase to break down bilirubin into colorless urobilinogen, which degrades into yellowish #urobilin, giving urine that infamous hue. While urobilin previously had an association with color of urine, enzyme that starts process producing urobilinogen was unknown.
https://arstechnica.com/science/2024/01/gotta-go-weve-finally-found-out-what-makes-urine-yellow/

This is seriously cool! With all the fake tech hype all around, let's not forget there is real amazing progress happening.

#FDA Approves First #CRISPR Gene Editing Treatment for #SickleCellDisease

https://www.scientificamerican.com/article/fda-approves-first-crispr-gene-editing-treatment-for-sickle-cell-disease/

"physicians remove a person’s own bone marrow #StemCells, edit them, destroy the untreated #BoneMarrow and then reinfuse the edited cells... Cas9 deactivates BCL11A in stem cells and they begin producing the fetal #hemoglobin and creating #RedBloodCells with a normal shape"

#US #approves first #geneediting #treatment, #Casgevy, for #SickleCellDisease.

#SickleCell, an inherited #blood #disorder, causes #redbloodcells to become misshapen half moons that get stuck inside #blood #vessels, #restricting #bloodflow and causing what are known as #paincrises.

#Women #Transgender #LGBTQ #LGBTQIA #Health #Healthcare #Progress #BlackMastodon

https://www.cnbc.com/2023/12/08/casgevy-first-crispr-gene-editing-treatment-approved-in-us.html

First CRISPR-Based Therapies For Sickle Cell Disease and Beta Thalassemia Approved In The UK - The gene-therapy-based treatment called Casgevy was recently approved in the UK, m... - https://hackaday.com/2023/11/19/first-crispr-based-therapies-for-sickle-cell-disease-and-beta-thalassemia-approved-in-the-uk/ #redbloodcells #gene-therapy #crisprcas9 #hemoglobin #science #crispr

For #American #Science Peeps!

#USPS has new #stamps!

Twenty different images of #microscopic #photography, including #RedBloodCells, #Macaw #feathers, legs of #barnacles, #mouse #neurons and more!

I'm tempted to get them just for decoration.

They are #ForeverStamps, always equivalent to the current first-class-mail one oz price.

https://store.usps.com/store/product/buy-stamps/life-magnified-stamps-S_484004

.@MadelineDans &co show that sulfonylpiperazines reduce #actin polymerization in the #malaria parasite via a #profilin-mediated mechanism, preventing invasion of #RedBloodCells, and demonstrating that actin-profilin interaction is druggable #PLOSBiology https://plos.io/3zZedEY

.@MadelineDans &co show that sulfonylpiperazines reduce #actin polymerization in the #malaria parasite via a #profilin-mediated mechanism, preventing invasion of #RedBloodCells, and demonstrating that actin-profilin interaction is druggable #PLOSBiology https://plos.io/3zZedEY

.@MadelineDans &co show that sulfonylpiperazines reduce #actin polymerization in the #malaria parasite via a #profilin-mediated mechanism, preventing invasion of #RedBloodCells, and demonstrating that actin-profilin interaction is druggable #PLOSBiology https://plos.io/3zZedEY

Glassfrogs hide red #blood #cells in their liver to become transparent https://phys.org/news/2022-12-glassfrogs-red-blood-cells-liver.html

Glassfrogs conceal blood in their liver to maintain transparency https://www.science.org/doi/10.1126/science.abl6620

When #glassfrogs are resting, their #muscles and #skin become #transparent, and their #bones, #eyes and internal #organs are all that's visible. If these #frogs are awake, stressed or under #anesthesia their #CirculatorySystem is full of #RedBloodCells and they are opaque.