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#toxicology

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Bongolian

Darren Incorvaia: The fruit fly revolutionized biology. Now it’s boosting science in #Africa: Researchers across the continent are turning to the humble insects for experiments

"When Amos Abolaji returned to Nigeria from a year abroad, he brought home a strange souvenir — two jars full of fruit flies.

The biochemist had been conducting postdoctoral research at the Federal University of Santa Maria in Brazil on the health effects of certain pollutants. He had used laboratory rodents while working on his Ph.D. in #Nigeria and wasn’t previously exposed to the use of fruit flies. But when Abolaji joined toxicologist Joao Batista Teixeira da Rocha’s lab in Brazil, 'he told me he stopped the use of rodents for research.' Rocha had switched to using the fruit fly Drosophila melanogaster."

#fruitfly #entomology #biochemistry #toxicology #research
sciencenews.org/article/fruit-

Science News · The fruit fly revolutionized biology. Now it’s boosting science in AfricaAfrican researchers are using Drosophila melanogaster fruit flies to advance studies of genetics, biomedicine, developmental biology, toxicology and more.
Public
BellingenNSW

Recycling toxic car tyres through the body and the environment

When tyres are used, tiny particles of rubber are released and accumulate on road surfaces. These particles can be washed away by rainwater into storm drains, ultimately ending up in nearby water bodies such as rivers, lakes, and oceans.The particles contribute to a range of negative health impacts including heart, lung, developmental, reproductive, and cancer outcomes.

Tyre wear particle (TWP) are generated by contact between tyre and road surface during driving, acceleration and braking.>
sciencedirect.com/science/arti

Tires are a complex source of pollutants including whole tires, particles, compounds, and chemicals. As they wear, tires emit pollutants via atmospheric, aquatic, and terrestrial pathways.>
sciencedirect.com/science/arti

Tyre wear particle emissions have outweighed those from the exhaust and are potential for microplastic pollution.>
sciencedirect.com/science/arti

Tyre wear particles pollute the environment, the air we breathe, the water run-off from roads and has compounding effects on waterways and agriculture.
imperial.ac.uk/news/243333/pri
#cars #roads #vehicles #EVs #speed #machinery #pollution #FossilFuels #microplastics #harm #regulation #automobility #TRWP #TWP #toxicology #ecotoxicity #PAH #water #runoff #waste #food #health #risk

SUV parking on tree roots, Church St. Bellingen
Public
Jennifer Lin

Here's a new post about cytochrome P450 (CYP) and small drug molecules, specifically on CYP3A4 and 2D6 inhibitors. At one point I thought I might not be able to finish it properly, glad I did, many thanks to @baoilleach

jhylin.github.io/Data_in_life_

#metabolism #toxicology #structural_alerts #pandas #RDKit
#cheminformatics #Python #pyladies

jhylin.github.ioHome - Cytochrome P450 and small drug molecules
Public
Center for Open Science

Calling all toxicology and environmental health researchers! Join us on Feb. 29, 2024, at 11 am ET for a webinar on "Preregistration Templates as a New Addition to the Evidence-Based Toxicology Toolbox."

Learn how these templates streamline research methods, enhance collaboration, and boost credibility. Don't miss the chance to submit your templates to an EBT Special Issue! Register now: bit.ly/3SXlrn8.

#OpenScience#Toxicology#EnvironmentalHealth
Public
Denis Meuthen

New📜paper out in Aquatic Toxicology. In zebrafish, maternal exposure to the plastic additive Bisphenol S (a common replacement for BPA in many "BPA-free" products) negatively affects their male offspring. Similar to the effects of maternal estrogen exposure, male offspring hid less, decreased their shoal density in the presence of a predatory threat and reduced expression of multiple serotonin receptor genes.
authors.elsevier.com/c/1iNej,3
#environment #toxicology #ecology @academicchatter

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