Rhyothemis<p><span class="h-card"><a href="https://mastodon.social/@inkican" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>inkican</span></a></span> </p><p>Interesting, but the article is frustratingly vague about the mechanism of action.</p><p>The drug/MoA is probably the same as in this article⬇️ <br>"PnPP-19 potentiates erection, in vivo and ex vivo, via NO/cGMP pathway, does not affect sodium channels or rat heart, and shows no toxicity and low immunogenicity, what makes it a very promising candidate as a novel drug in the therapy of erectile dysfunction."</p><p><a href="http://dx.doi.org/10.1016/j.juro.2015.06.081" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">http://</span><span class="ellipsis">dx.doi.org/10.1016/j.juro.2015</span><span class="invisible">.06.081</span></a></p><p>~<br>NO is antimicrobial and it's possible this drug could be used for other purposes.</p><p><a href="https://zeroes.ca/tags/NitricOxide" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>NitricOxide</span></a> <a href="https://zeroes.ca/tags/cGMP" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cGMP</span></a> <a href="https://zeroes.ca/tags/vasodilators" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>vasodilators</span></a> <a href="https://zeroes.ca/tags/DrugDevelopment" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>DrugDevelopment</span></a> <a href="https://zeroes.ca/tags/NaturalProducts" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>NaturalProducts</span></a> <a href="https://zeroes.ca/tags/BZ371A" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>BZ371A</span></a></p>